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2025 Lexus IS 500
Lexus IS — the model line, not this exact trim. Photo: TTTNIS · CC0 · Wikimedia Commons

2025 Lexus IS 500

Lexus · Rear-Wheel Drive · 5.0 L 8-cyl

★★★★★ NHTSA overall safety

See it on fueleconomy.gov
Model year2025
Combined MPG20
City MPG17
Highway MPG25
Annual fuel cost$4,100

Against the 402 fuel-efficient cars

Combined MPG 20 MPGbest 55 · avg 26
Annual fuel cost $4,100best $1,200 · avg $3,409

Bars are scaled to the best in the list; the mark shows the list average. Lower is better for fuel cost; higher is better for the rest. All figures are the EPA's.

Safety ratings

Overall★★★★★
Frontal crash★★★★★
Side crash★★★★★
Rollover★★★★★
Recalls on record0

From NHTSA's 5-Star Safety Ratings for this model year (2025 Lexus IS 500 4 DR RWD).

Summary

2025 Lexus IS 500 by Lexus. The figures below are from US EPA fueleconomy.gov, with the page each one came from.

Details

Model year
2025fueleconomy.gov · 3 Oct 2026

Efficiency

Combined MPG
20fueleconomy.gov · 3 Oct 2026
City MPG
17fueleconomy.gov · 3 Oct 2026
Highway MPG
25fueleconomy.gov · 3 Oct 2026

Running cost

Annual fuel cost
$4,100fueleconomy.gov · 3 Oct 2026
CO₂ (tailpipe)
451 g/mifueleconomy.gov · 3 Oct 2026

Car

Body
Carfueleconomy.gov · 3 Oct 2026
EPA class
Compact Carsfueleconomy.gov · 3 Oct 2026
Drive
Rear-Wheel Drivefueleconomy.gov · 3 Oct 2026

Powertrain

Engine
5.0 L 8-cylfueleconomy.gov · 3 Oct 2026
Transmission
Automatic (S8)fueleconomy.gov · 3 Oct 2026
Fuel
Gasolinefueleconomy.gov · 3 Oct 2026

More lexus cars

See the list
2026 Lexus ES 350e (19 inch Wheels) 2026 · Front-Wheel Drive · 167 kW AC Synchronous Combined MPGe127EPA range307 miAnnual fuel cost$600 2026 Lexus ES 350e (21 inch Wheels) 2026 · Front-Wheel Drive · 167 kW AC Synchronous Combined MPGe121EPA range292 miAnnual fuel cost$600 2026 Lexus ES 350h 2026 · Front-Wheel Drive · 2.5 L 4-cyl Combined MPG46Annual fuel cost$1,800 2026 Lexus ES 350h AWD 2026 · All-Wheel Drive · 2.5 L 4-cyl Combined MPG44Annual fuel cost$1,850 2026 Lexus ES 500e AWD (19 inch Wheels) 2026 · All-Wheel Drive · 88 and 167 kW AC Synchronous Combined MPGe114EPA range276 miAnnual fuel cost$700 2026 Lexus ES 500e AWD (21 inch Wheels) 2026 · All-Wheel Drive · 88 and 167 kW AC Synchronous Combined MPGe112EPA range272 miAnnual fuel cost$700

Where it ranks on CarCody

Sources