Photo: Lexus IS by TTTNIS, CC0, via Wikimedia Commons. It shows the model, not always this exact version.
Lexus · model year 2026
2026 Lexus IS 350
Compact · Rear-Wheel Drive · Gas · EPA class: Compact Cars
Where it places
- 72 Fuel-efficient compact cars
Ordered by combined MPG #72 of 86 - 239 Fuel-efficient cars
Ordered by combined MPG #239 of 401 - 08 Lexus cars
Every model year, newest first #8 of 767 - 641 2026 cars and trucks
Every car of that year, A to Z #641 of 1,172 - 1409 Gas and hybrid cars by fuel cost
Ordered by fuel a year #1409 of 2,158
Against fuel-efficient compact cars
The CarCody take
The 2026 Lexus IS 350 is a rear-wheel-drive gasoline car with a 3.5 L 6-cyl engine. It uses an automatic (S8) transmission and returns EPA fuel economy of 19 MPG in the city, 27 MPG on the highway and 22 MPG combined. The EPA annual fuel cost is $3,750, and tailpipe CO2 emissions are 403 g per mile. The IS 350 is classified as a Compact Car. Buyers considering this Lexus can use the three MPG ratings to see its listed city, highway and combined fuel economy, while the annual estimate gives a separate cost measure. Its rear-wheel-drive layout and six-cylinder engine are further defining facts for comparing this model with other cars under consideration. The entry’s figures describe a gasoline-powered car and its fuel use, without implying other equipment or capabilities beyond those listed.
Good to know
- 27 MPG highway.
- 3.5 L 6-cyl engine.
- Automatic (S8) transmission.
- Rear-wheel drive.
Watch for
- 19 MPG city and 22 MPG combined.
- EPA annual fuel cost is $3,750.
- Tailpipe CO2 is 403 g per mile.
Who it suits. It suits compact-car shoppers seeking a gasoline-powered, rear-wheel-drive model with a six-cylinder engine. Buyers weighing operating expenses can use its 22 MPG combined rating and $3,750 EPA annual fuel cost.
The IS 350 is a rear-wheel-drive compact car with a 3.5 L six-cylinder engine. Its 22 MPG combined rating and $3,750 EPA annual fuel cost are central considerations for shoppers focused on fuel use.
Every figure on record
- Combined MPG
- 22 MPG
- City MPG
- 19 MPG
- Highway MPG
- 27 MPG
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 403 g per mile
- Model year
- 2026
- Body
- Car
- EPA size class
- Compact Cars
- Drive
- Rear-Wheel Drive
- Engine
- 3.5 L 6-cyl
- Transmission
- Automatic (S8)
- Fuel
- Gasoline
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24 MPG · $3,400 fuel a year
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24 MPG · $3,400 fuel a year
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23 MPG · $3,550 fuel a year
2026 Mercedes-Benz AMG CLA45 S 4matic
23 MPG · $3,550 fuel a year 2027 Genesis G70 AWD
23 MPG · $3,550 fuel a year 2026 Cadillac CT4 V AWD
23 MPG · $3,550 fuel a year
2026 Mercedes-Benz AMG C43 4matic
22 MPG · $3,750 fuel a year