2026 Lexus IS 350

The CarCody take

The 2026 Lexus IS 350 is a gasoline compact car with rear-wheel drive, a 3.5-liter six-cylinder engine and an automatic eight-speed transmission. Its EPA rating is 22 MPG combined, with 19 MPG in city driving and 27 MPG on the highway. The EPA annual fuel-cost estimate is $3,750.

Who it suits. Drivers wanting a rear-wheel-drive compact gasoline car Mixed city and highway driving Buyers comfortable with the EPA fuel-cost estimate

What it is

The 2026 Lexus IS 350 is a compact car that runs on gasoline.

Its defining EPA figure is 22 MPG combined. That combines the 19 MPG city rating with the 27 MPG highway rating.

The numbers

City driving is rated at 19 MPG, while highway driving is rated at 27 MPG. The combined figure is 22 MPG.

Those ratings describe different driving patterns: the city number is the lower estimate for stop-and-go use, and the highway number is higher for steady-speed travel.

What it costs to run

The EPA annual fuel-cost estimate is $3,750. That gives you a yearly gasoline budget figure for this car's rated efficiency.

Actual spending changes with how much you drive and the gasoline price where you live.

How it compares

As a compact car, the IS 350's 22 combined MPG can be weighed against other models in the compact-car fuel chart. Its 19 city and 27 highway ratings show how its estimate changes with the type of driving.

You can also place it beside other entries in the broader fuel-efficiency chart or review other Lexus cars.

Who it suits

The IS 350 fits a driver who wants a gasoline compact car with rear-wheel drive and accepts the fuel budget that comes with a 22 MPG combined rating.

Its split ratings may make sense for someone whose driving includes both city streets and highways.

Trade-offs

The 3.5-liter six-cylinder engine and rear-wheel-drive layout define the car, while the EPA estimates are 19 MPG in the city and 27 MPG on the highway.

Those numbers mean more fuel use in stop-and-go driving than on the highway, with a combined estimate of 22 MPG and an EPA annual fuel-cost figure of $3,750.

Verdict

Choose the 2026 Lexus IS 350 if a compact gasoline car with rear-wheel drive matches your priorities. The EPA numbers give you a clear budget marker: 22 MPG combined, rising to 27 MPG on the highway and falling to 19 MPG in city traffic. Its 3.5-liter six-cylinder engine and eight-speed automatic transmission complete the powertrain description. Compare those figures with other compact cars before deciding whether this fuel cost fits your driving.