2025 Lexus IS 500 vs 2026 Mercedes-Benz AMG C43 4matic
| EPA figure | 2025 Lexus IS 500 | 2026 Mercedes-Benz AMG C43 4matic |
|---|---|---|
| Model year | 2025 | 2026 |
| Body · drive | Compact · Rear-Wheel Drive · Gas | Compact · All-Wheel Drive · Hybrid |
| Combined MPG | 20 | 22 |
| City / highway MPG | 17 / 25 | 19 / 27 |
| Fuel a year | $4,100 | $3,750 |
| Tailpipe CO₂ (g/mi) | 451 | 405 |
| Engine | 5.0 L 8-cyl | 2.0 L 4-cyl turbo |
| Transmission | Automatic (S8) | Automatic 9-spd |
▲ marks the better official figure on that line: more range, MPG or MPGe; less fuel cost or CO₂. From fueleconomy.gov.