2026 Mercedes-Benz GLS450 4matic
Fuel economy & running costsHybrid
#116 of 2,118 · Mercedes-Benz cars

2026 Mercedes-BenzGLS450 4matic

Standard Sport Utility Vehicle 4WD · All-Wheel Drive · 3.0 L 6-cyl turbo supercharged

21MPGcombined
19city
24highway
A year of fuel$3,900
CO₂ from the tailpipe428 g/mi
Figures from the EPA label (fueleconomy.gov), the same as on the car's window sticker.

Against the 2,118 Mercedes-Benz cars

Combined MPG 21 MPGbest 33 · avg 20
Annual fuel cost $3,900best $600 · avg $4,245

Bars are scaled to the best in the list; the mark shows the list average. Lower is better for fuel cost; higher is better for the rest. All figures are the EPA's.