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2025 Lexus LS 500
Lexus LS — the model line, not this exact trim. Photo: HJUdall · CC0 · Wikimedia Commons

2025 Lexus LS 500

Lexus · Rear-Wheel Drive · 3.4 L 6-cyl turbo

See it on fueleconomy.gov
Model year2025
Combined MPG22
City MPG18
Highway MPG29
Annual fuel cost$3,750

Against the 402 fuel-efficient cars

Combined MPG 22 MPGbest 55 · avg 26
Annual fuel cost $3,750best $1,200 · avg $3,409

Bars are scaled to the best in the list; the mark shows the list average. Lower is better for fuel cost; higher is better for the rest. All figures are the EPA's.

Summary

2025 Lexus LS 500 by Lexus. The figures below are from US EPA fueleconomy.gov, with the page each one came from.

Details

Model year
2025fueleconomy.gov · 3 Oct 2026

Efficiency

Combined MPG
22fueleconomy.gov · 3 Oct 2026
City MPG
18fueleconomy.gov · 3 Oct 2026
Highway MPG
29fueleconomy.gov · 3 Oct 2026

Running cost

Annual fuel cost
$3,750fueleconomy.gov · 3 Oct 2026
CO₂ (tailpipe)
404 g/mifueleconomy.gov · 3 Oct 2026

Car

Body
Carfueleconomy.gov · 3 Oct 2026
EPA class
Midsize Carsfueleconomy.gov · 3 Oct 2026
Drive
Rear-Wheel Drivefueleconomy.gov · 3 Oct 2026

Powertrain

Engine
3.4 L 6-cyl turbofueleconomy.gov · 3 Oct 2026
Transmission
Automatic (S10)fueleconomy.gov · 3 Oct 2026
Fuel
Gasolinefueleconomy.gov · 3 Oct 2026

More lexus cars

See the list
2026 Lexus ES 350e (19 inch Wheels) 2026 · Front-Wheel Drive · 167 kW AC Synchronous Combined MPGe127EPA range307 miAnnual fuel cost$600 2026 Lexus ES 350e (21 inch Wheels) 2026 · Front-Wheel Drive · 167 kW AC Synchronous Combined MPGe121EPA range292 miAnnual fuel cost$600 2026 Lexus ES 350h 2026 · Front-Wheel Drive · 2.5 L 4-cyl Combined MPG46Annual fuel cost$1,800 2026 Lexus ES 350h AWD 2026 · All-Wheel Drive · 2.5 L 4-cyl Combined MPG44Annual fuel cost$1,850 2026 Lexus ES 500e AWD (19 inch Wheels) 2026 · All-Wheel Drive · 88 and 167 kW AC Synchronous Combined MPGe114EPA range276 miAnnual fuel cost$700 2026 Lexus ES 500e AWD (21 inch Wheels) 2026 · All-Wheel Drive · 88 and 167 kW AC Synchronous Combined MPGe112EPA range272 miAnnual fuel cost$700

Where it ranks on CarCody

Sources