From fuel-efficient midsize cars
Alternatives to the 2025 Lexus LS 500
The cars next to it on fuel-efficient midsize cars: the same kind of car, with official EPA figures close to its own. Open any of them for its window sticker, or put two side by side.
- 80
Combined MPG· $3,400 fuel a year24 MPG$3,400fuel a year - 81 Combined MPG· $3,400 fuel a year24 MPG$3,400fuel a year
- 82
2026 Mercedes-Benz AMG E53 Hybrid 4matic Plus
Midsize · All-Wheel Drive · Plug-in hybrid
Plug-in hybrid 3.0 L 6-cyl turbo 22 city · 27 hwyCombined MPG· $3,400 fuel a year24 MPG$3,400fuel a year - 83
Combined MPG· $3,550 fuel a year23 MPG$3,550fuel a year - 84 Combined MPG· $3,550 fuel a year23 MPG$3,550fuel a year
- 85
Combined MPG· $3,550 fuel a year23 MPG$3,550fuel a year - 87 Combined MPG· $3,750 fuel a year22 MPG$3,750fuel a year
- 88
Combined MPG· $3,750 fuel a year22 MPG$3,750fuel a year - 89
Combined MPG· $3,750 fuel a year22 MPG$3,750fuel a year - 90
Combined MPG· $3,750 fuel a year22 MPG$3,750fuel a year - 91
Combined MPG· $3,750 fuel a year22 MPG$3,750fuel a year - 92 Combined MPG· $3,900 fuel a year21 MPG$3,900fuel a year