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2025 Lexus LS 500 vs 2026 Mercedes-Benz AMG E53 Hybrid 4matic Plus

EPA figure2025 Lexus LS 5002026 Mercedes-Benz AMG E53 Hybrid 4matic Plus
Model year20252026
Body · driveMidsize · Rear-Wheel Drive · GasMidsize · All-Wheel Drive · Plug-in hybrid
EPA range—44 mi
Combined MPGe—60
Combined MPG2224
City / highway MPG18 / 2922 / 27
Fuel a year$3,750$3,400
Tailpipe CO₂ (g/mi)404115
Engine3.4 L 6-cyl turbo3.0 L 6-cyl turbo
TransmissionAutomatic (S10)Automatic 9-spd

▲ marks the better official figure on that line: more range, MPG or MPGe; less fuel cost or CO₂. From fueleconomy.gov.