Gas cars · 105 cars · page 3 of 5
Most Fuel-Efficient Midsize Cars in 2026
- 51
Combined MPG· $2,400 fuel a year28 MPG$2,400fuel a year - 52
Combined MPG· $2,400 fuel a year28 MPG$2,400fuel a year - 53
Combined MPG· $2,950 fuel a year28 MPG$2,950fuel a year - 54
Combined MPG· $2,400 fuel a year28 MPG$2,400fuel a year - 55
Combined MPG· $2,400 fuel a year28 MPG$2,400fuel a year - 56
2027 Mercedes-Benz E350
Midsize · Rear-Wheel Drive · Hybrid
Hybrid 2.0 L 4-cyl turbo 25 city · 33 hwyCombined MPG· $2,950 fuel a year28 MPG$2,950fuel a year - 57
Combined MPG· $2,400 fuel a year28 MPG$2,400fuel a year - 58
2027 BMW 540i xDrive Sedan
Midsize · All-Wheel Drive · Hybrid
Hybrid 3.0 L 6-cyl turbo 26 city · 32 hwyCombined MPG· $2,950 fuel a year28 MPG$2,950fuel a year - 59
2027 Mercedes-Benz E350 4matic
Midsize · All-Wheel Drive · Hybrid
Hybrid 2.0 L 4-cyl turbo 24 city · 33 hwyCombined MPG· $3,050 fuel a year27 MPG$3,050fuel a year - 60
Combined MPG· $3,050 fuel a year27 MPG$3,050fuel a year - 61 Combined MPG· $2,500 fuel a year27 MPG$2,500fuel a year
- 62
2025 Audi A5 Sportback S line quattro
Midsize · All-Wheel Drive · Hybrid
Hybrid 2.0 L 4-cyl turbo 23 city · 32 hwyCombined MPG· $3,150 fuel a year26 MPG$3,150fuel a year - 63 Combined MPG· $3,150 fuel a year26 MPG$3,150fuel a year
- 64
Combined MPG· $2,600 fuel a year26 MPG$2,600fuel a year - 65 Combined MPG· $2,600 fuel a year26 MPG$2,600fuel a year
- 66
Combined MPG· $3,150 fuel a year26 MPG$3,150fuel a year - 67
2025 Volvo S90 B6 AWD
Midsize · All-Wheel Drive · Hybrid
Hybrid 2.0 L 4-cyl turbo supercharged 23 city · 31 hwyCombined MPG· $3,150 fuel a year26 MPG$3,150fuel a year - 68
Combined MPG· $3,150 fuel a year26 MPG$3,150fuel a year - 69 Combined MPG· $3,150 fuel a year26 MPG$3,150fuel a year
- 70 Combined MPG· $3,150 fuel a year26 MPG$3,150fuel a year
- 71 Combined MPG· $2,700 fuel a year25 MPG$2,700fuel a year
- 72 Combined MPG· $2,700 fuel a year25 MPG$2,700fuel a year
- 73
2027 Mercedes-Benz E450 4matic
Midsize · All-Wheel Drive · Hybrid
Hybrid 3.0 L 6-cyl turbo supercharged 22 city · 31 hwyCombined MPG· $3,300 fuel a year25 MPG$3,300fuel a year - 74 Combined MPG· $3,300 fuel a year25 MPG$3,300fuel a year
- 75
Combined MPG· $3,300 fuel a year25 MPG$3,300fuel a year
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- Audi A5 · Alexander Migl · CC BY-SA 4.0 · Wikimedia Commons
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- Audi A7 · Alexander Migl · CC BY-SA 4.0 · Wikimedia Commons
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- Volvo S90 · Alexander Migl · CC BY-SA 4.0 · Wikimedia Commons
- Alfa Romeo Giulia · Rex Gray from Southern California · CC BY 2.0 · Wikimedia Commons
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- Volvo S90 · Alexander Migl · CC BY-SA 4.0 · Wikimedia Commons
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- Mercedes-Benz E-Class · Alexander Migl · CC BY-SA 4.0 · Wikimedia Commons
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- Mercedes-Benz E-Class · Alexander Migl · CC BY-SA 4.0 · Wikimedia Commons
- Volkswagen Golf GTI · Charles01 · CC BY-SA 4.0 · Wikimedia Commons
- Volkswagen Golf GTI · Charles01 · CC BY-SA 4.0 · Wikimedia Commons