Photo: Mercedes-Benz S-Class by David Adam Kess, CC BY-SA 4.0, via Wikimedia Commons. It shows the model, not always this exact version.
Mercedes-Benz · model year 2025
2025 Mercedes-Benz S580e 4matic
Large · All-Wheel Drive · Plug-in hybrid · EPA class: Large Cars
EPA figures · 2025fueleconomy.gov
23MPG combined
20/29MPG city / highway
$3,550fuel a year
106 g CO₂ per mile 3.0 L 6-cyl turbo Automatic 9-spd
This car on fueleconomy.gov, read 2 October 2026. Your own figures depend on how and where you drive.
Where it places
- 31 Plug-in hybrids
Ordered by combined MPG #31 of 73 - 62 Fuel-efficient large cars
Ordered by combined MPG #62 of 114 - 223 Fuel-efficient cars
Ordered by combined MPG #223 of 401 - 885 2025 cars and trucks
Every car of that year, A to Z #885 of 1,273 - 500 Fuel-efficient AWD and 4WD cars
Ordered by combined MPG #500 of 1,362 - 211 Mercedes-Benz cars
Every model year, newest first #211 of 2,118 - 1194 Gas and hybrid cars by fuel cost
Ordered by fuel a year #1194 of 2,158
Against plug-in hybrids
Chart average 27 miBest 54 mi
Chart average 59 MPGeBest 127 MPGe
Chart average 24 MPGBest 52 MPG
Lowest on the chart $1,300Chart average $3,575
Every figure on record
- Combined MPG
- 23 MPG
- City MPG
- 20 MPG
- Highway MPG
- 29 MPG
- Combined MPGe
- 63 MPGe
- EPA range
- 48 miles
- Energy use
- 53 kWh per 100 miles
- Annual fuel cost
- $3,550
- Tailpipe CO₂
- 106 g per mile
- Charge time at 240 V
- 2.8 hours
- Model year
- 2025
- Body
- Car
- EPA size class
- Large Cars
- Drive
- All-Wheel Drive
- Engine
- 3.0 L 6-cyl turbo
- Transmission
- Automatic 9-spd
- Fuel
- Gasoline
Efficiency
Running cost
Charging
The car
Powertrain
Cars around it
2025 Mercedes-Benz GLC350e 4matic with EQ Hybrid Tech
25 MPG · $3,300 fuel a year
2027 BMW 550e xDrive Sedan
25 MPG · $3,300 fuel a year
2025 Mazda CX-70 4WD PHEV
25 MPG · $3,300 fuel a year
2025 Mazda CX-90 4WD PHEV
25 MPG · $3,300 fuel a year
2026 Mercedes-Benz AMG E53 Hybrid 4matic Plus
24 MPG · $3,400 fuel a year
2026 BMW 750e xDrive Sedan
24 MPG · $3,400 fuel a year
2025 Mercedes-Benz GLE450e 4matic
23 MPG · $3,550 fuel a year