Fuel economy & running costsHybrid
#208 of 2,118 · Mercedes-Benz cars
2025 Mercedes-BenzS500 4matic
Large Cars · All-Wheel Drive · 3.0 L 6-cyl turbo supercharged
24MPGcombined
21city
31highway
A year of fuel$3,400
CO₂ from the tailpipe364 g/mi
Figures from the EPA label (fueleconomy.gov), the same as on the car's window sticker.
Against the 2,118 Mercedes-Benz cars
Bars are scaled to the best in the list; the mark shows the list average. Lower is better for fuel cost; higher is better for the rest. All figures are the EPA's.
Summary
2025 Mercedes-Benz S500 4matic by Mercedes-Benz. The figures below are from US EPA fueleconomy.gov, with the page each one came from.
Details
- Model year
- 2025fueleconomy.gov · 3 Oct 2026
Efficiency
- Combined MPG
- 24fueleconomy.gov · 3 Oct 2026
- City MPG
- 21fueleconomy.gov · 3 Oct 2026
- Highway MPG
- 31fueleconomy.gov · 3 Oct 2026
Running cost
- Annual fuel cost
- $3,400fueleconomy.gov · 3 Oct 2026
- CO₂ (tailpipe)
- 364 g/mifueleconomy.gov · 3 Oct 2026
Car
- Body
- Carfueleconomy.gov · 3 Oct 2026
- EPA class
- Large Carsfueleconomy.gov · 3 Oct 2026
- Drive
- All-Wheel Drivefueleconomy.gov · 3 Oct 2026
Powertrain
- Engine
- 3.0 L 6-cyl turbo superchargedfueleconomy.gov · 3 Oct 2026
- Transmission
- Automatic 9-spdfueleconomy.gov · 3 Oct 2026
- Fuel
- Gasolinefueleconomy.gov · 3 Oct 2026
More Mercedes-Benz cars
See the listMercedes-Benz #1 2027 · Mercedes-Benz AMG CLE53 4matic Plus (convertible) 22Combined MPG $3,750Fuel / year Mercedes-Benz #2 2027 · Mercedes-Benz AMG CLE53 4matic Plus (coupe) 23Combined MPG $3,550Fuel / year 
#3 2027 · Mercedes-Benz AMG G63 15Combined MPG $5,500Fuel / year 
#4 2027 · Mercedes-Benz AMG GLC53 4matic Plus 22Combined MPG $3,750Fuel / year #5 2027 · Mercedes-Benz AMG GLC53 4matic Plus (coupe) 22Combined MPG $3,750Fuel / year 
#6 2027 · Mercedes-Benz AMG GT 43 (coupe) 22Combined MPG $3,750Fuel / year
#3 2027 · Mercedes-Benz AMG G63 15Combined MPG $5,500Fuel / year #4 2027 · Mercedes-Benz AMG GLC53 4matic Plus 22Combined MPG $3,750Fuel / year #5 2027 · Mercedes-Benz AMG GLC53 4matic Plus (coupe) 22Combined MPG $3,750Fuel / year #6 2027 · Mercedes-Benz AMG GT 43 (coupe) 22Combined MPG $3,750Fuel / year Listed on CarCody
Sources
- fueleconomy.gov/feg/noframes/48193.shtml· checked 3 Oct 2026