Photo: Mercedes-Benz E-Class by Alexander Migl, CC BY-SA 4.0, via Wikimedia Commons. It shows the model, not always this exact version.
Mercedes-Benz · model year 2025
2025 Mercedes-Benz E350
Midsize · Rear-Wheel Drive · Hybrid · EPA class: Midsize Cars
EPA figures · 2025fueleconomy.gov
28MPG combined
25/33MPG city / highway
$2,950fuel a year
316 g CO₂ per mile 2.0 L 4-cyl turbo Automatic 9-spd
This car on fueleconomy.gov, read 2 October 2026. Your own figures depend on how and where you drive.
Where it places
Against gas and hybrid cars by fuel cost
Chart average 24 MPGBest 57 MPG
Lowest on the chart $1,200Chart average $3,426
Every figure on record
- Combined MPG
- 28 MPG
- City MPG
- 25 MPG
- Highway MPG
- 33 MPG
- Annual fuel cost
- $2,950
- Tailpipe CO₂
- 316 g per mile
- Model year
- 2025
- Body
- Car
- EPA size class
- Midsize Cars
- Drive
- Rear-Wheel Drive
- Engine
- 2.0 L 4-cyl turbo
- Transmission
- Automatic 9-spd
- Fuel
- Gasoline
Efficiency
Running cost
The car
Powertrain
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