From fuel-efficient midsize cars
Alternatives to the 2025 Lexus LS 500h AWD
The cars next to it on fuel-efficient midsize cars: the same kind of car, with official EPA figures close to its own. Open any of them for its window sticker, or put two side by side.
- 70
Combined MPG· $3,150 fuel a year26 MPG$3,150fuel a year - 71
Combined MPG· $2,700 fuel a year25 MPG$2,700fuel a year - 72 Combined MPG· $2,700 fuel a year25 MPG$2,700fuel a year
- 73
2027 Mercedes-Benz E450 4matic
Midsize · All-Wheel Drive · Hybrid
Hybrid 3.0 L 6-cyl turbo supercharged 22 city · 31 hwyCombined MPG· $3,300 fuel a year25 MPG$3,300fuel a year - 74
Combined MPG· $3,300 fuel a year25 MPG$3,300fuel a year - 75
Combined MPG· $3,300 fuel a year25 MPG$3,300fuel a year - 77
2027 BMW 550e xDrive Sedan
Midsize · All-Wheel Drive · Plug-in hybrid
Plug-in hybrid 3.0 L 6-cyl turbo 22 city · 28 hwyCombined MPG· $3,300 fuel a year25 MPG$3,300fuel a year - 78
Combined MPG· $3,400 fuel a year24 MPG$3,400fuel a year - 79
Combined MPG· $3,400 fuel a year24 MPG$3,400fuel a year - 80
Combined MPG· $3,400 fuel a year24 MPG$3,400fuel a year - 81 Combined MPG· $3,400 fuel a year24 MPG$3,400fuel a year
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2026 Mercedes-Benz AMG E53 Hybrid 4matic Plus
Midsize · All-Wheel Drive · Plug-in hybrid
Plug-in hybrid 3.0 L 6-cyl turbo 22 city · 27 hwyCombined MPG· $3,400 fuel a year24 MPG$3,400fuel a year