Fuel economy & running costsHybrid

2021 ToyotaSienna Hybrid 2WD

Minivan - 2WD · Front-Wheel Drive · 2.5 L 4-cyl

36MPGcombined

36city

36highway

A year of fuel$1,850

CO₂ from the tailpipe246 g/mi

Figures from the EPA label (fueleconomy.gov), the same as on the car's window sticker.

See it on fueleconomy.gov

Against the 2,645 toyota cars

Combined MPG 36 MPGbest 74 · avg 24

Annual fuel cost $1,850best $550 · avg $3,100

Bars are scaled to the best in the list; the mark shows the list average. Lower is better for fuel cost; higher is better for the rest. All figures are the EPA's.

Summary

2021 Toyota Sienna Hybrid 2WD by Toyota. The figures below are from US EPA fueleconomy.gov, with the page each one came from.

Details

Model year: 2021fueleconomy.gov · 3 Oct 2026

Efficiency

Combined MPG: 36fueleconomy.gov · 3 Oct 2026
City MPG: 36fueleconomy.gov · 3 Oct 2026
Highway MPG: 36fueleconomy.gov · 3 Oct 2026

Running cost

Annual fuel cost: $1,850fueleconomy.gov · 3 Oct 2026
CO₂ (tailpipe): 246 g/mifueleconomy.gov · 3 Oct 2026

Car

Body: Minivanfueleconomy.gov · 3 Oct 2026
EPA class: Minivan - 2WDfueleconomy.gov · 3 Oct 2026
Drive: Front-Wheel Drivefueleconomy.gov · 3 Oct 2026

Powertrain

Engine: 2.5 L 4-cylfueleconomy.gov · 3 Oct 2026
Transmission: Automatic (AV-S6)fueleconomy.gov · 3 Oct 2026
Fuel: Gasolinefueleconomy.gov · 3 Oct 2026

More toyota cars

See the list

Toyota #1 2027 · Toyota bZ AWD 288 miEPA range $650Fuel / year Toyota #2 2027 · Toyota bZ AWD LIMITED 278 miEPA range $650Fuel / year Toyota #3 2027 · Toyota bZ (energy capacity 191 Ah) 314 miEPA range $550Fuel / year Toyota #4 2027 · Toyota bZ (energy capacity 200 Ah) 236 miEPA range $600Fuel / year Toyota #5 2027 · Toyota bZ LIMITED 299 miEPA range $600Fuel / year Toyota #6 2027 · Toyota bZ Woodland AWD 235/60R18 281 miEPA range $650Fuel / year

Listed on CarCody

Toyota Cars: Every Model and Year With MPG2645 listed

Sources

fueleconomy.gov/feg/noframes/43470.shtml· checked 3 Oct 2026