Photo: Mercedes-Benz E-Class by Alexander Migl, CC BY-SA 4.0, via Wikimedia Commons. It shows the model, not always this exact version.
Mercedes-Benz · model year 2016
2016 Mercedes-Benz E350 4matic
Midsize · 4-Wheel Drive · Gas · EPA class: Midsize Cars
EPA figures · 2016fueleconomy.gov
23MPG combined
20/27MPG city / highway
$3,550fuel a year
384 g CO₂ per mile 3.5 L 6-cyl Automatic 7-spd
This car on fueleconomy.gov, read 2 October 2026. Your own figures depend on how and where you drive.
Where it places
Every figure on record
- Combined MPG
- 23 MPG
- City MPG
- 20 MPG
- Highway MPG
- 27 MPG
- Annual fuel cost
- $3,550
- Tailpipe CO₂
- 384 g per mile
- Model year
- 2016
- Body
- Car
- EPA size class
- Midsize Cars
- Drive
- 4-Wheel Drive
- Engine
- 3.5 L 6-cyl
- Transmission
- Automatic 7-spd
- Fuel
- Gasoline
Efficiency
Running cost
The car
Powertrain
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20 MPG · $4,100 fuel a year 2016 Mercedes-Benz E350
23 MPG · $3,550 fuel a year 2016 Mercedes-Benz E350
23 MPG · $3,550 fuel a year 2016 Mercedes-Benz E350 4matic
23 MPG · $3,550 fuel a year