2006 Isuzui-350 Crew Cab 4WD

Standard Pickup Trucks 4WD · 4-Wheel or All-Wheel Drive · 3.5 L 5-cyl

17MPGcombined

16city

21highway

A year of fuel$3,950

CO₂ from the tailpipe522.8 g/mi

Figures from the EPA label (fueleconomy.gov), the same as on the car's window sticker.

See it on fueleconomy.gov

Against the 434 isuzu cars

Combined MPG 17 MPGbest 35 · avg 19

Annual fuel cost $3,950best $1,900 · avg $3,730

Bars are scaled to the best in the list; the mark shows the list average. Lower is better for fuel cost; higher is better for the rest. All figures are the EPA's.

Summary

2006 Isuzu i-350 Crew Cab 4WD by Isuzu. The figures below are from US EPA fueleconomy.gov, with the page each one came from.

Details

Model year: 2006fueleconomy.gov · 3 Oct 2026

Efficiency

Combined MPG: 17fueleconomy.gov · 3 Oct 2026
City MPG: 16fueleconomy.gov · 3 Oct 2026
Highway MPG: 21fueleconomy.gov · 3 Oct 2026

Running cost

Annual fuel cost: $3,950fueleconomy.gov · 3 Oct 2026
CO₂ (tailpipe): 522.8 g/mifueleconomy.gov · 3 Oct 2026

Car

Body: Pickupfueleconomy.gov · 3 Oct 2026
EPA class: Standard Pickup Trucks 4WDfueleconomy.gov · 3 Oct 2026
Drive: 4-Wheel or All-Wheel Drivefueleconomy.gov · 3 Oct 2026

Powertrain

Engine: 3.5 L 5-cylfueleconomy.gov · 3 Oct 2026
Transmission: Automatic 4-spdfueleconomy.gov · 3 Oct 2026
Fuel: Gasolinefueleconomy.gov · 3 Oct 2026

More isuzu cars

See the list

#1 2009 · Isuzu Ascender 5-passenger 4WD 16Combined MPG $4,200Fuel / year

#2 2008 · Isuzu Ascender 5-passenger 2WD 16Combined MPG $4,200Fuel / year

#3 2008 · Isuzu Ascender 5-passenger 4WD 16Combined MPG $4,200Fuel / year Isuzu #4 2008 · Isuzu i-290 Extended Cab 2WD 20Combined MPG $3,350Fuel / year Isuzu #5 2008 · Isuzu i-290 Extended Cab 2WD 20Combined MPG $3,350Fuel / year Isuzu #6 2008 · Isuzu i-370 Crew Cab 2WD 18Combined MPG $3,700Fuel / year

Listed on CarCody

Isuzu Cars: Every Model and Year With MPG434 listed

Sources

fueleconomy.gov/feg/noframes/22282.shtml· checked 3 Oct 2026