GMC
Fuel economy & running costsGasoline
#1459 of 2,900 · GMC cars

2000 GMCSafari 2WD (cargo)

Vans, Cargo Type · Rear-Wheel Drive · 4.3 L 6-cyl

17MPGcombined
15city
20highway
A year of fuel$3,950
CO₂ from the tailpipe522.8 g/mi
Figures from the EPA label (fueleconomy.gov), the same as on the car's window sticker.

Against the 2,900 GMC cars

Combined MPG 17 MPGbest 32 · avg 17
Annual fuel cost $3,950best $900 · avg $4,328

Bars are scaled to the best in the list; the mark shows the list average. Lower is better for fuel cost; higher is better for the rest. All figures are the EPA's.

Summary

The 2000 GMC Safari 2WD (cargo) is a gasoline van in the EPA Vans, Cargo Type class. It has rear-wheel drive, a 4.3 L 6-cylinder engine and a four-speed automatic transmission. The listed fuel economy is 15 MPG in city driving and 20 MPG on the highway, or 17 MPG combined. Its EPA annual fuel cost is $3,950, and its tailpipe CO2 figure is 522.76 g per mile. This entry is identified as the cargo version of the Safari, with Safari Cargo listed as its base model. Those details help fleet operators and other buyers compare its basic vehicle configuration and stated fuel use without conflating it with a passenger-car entry.

Who it is for

This cargo van suits buyers or fleet operators looking for a gasoline vehicle with rear-wheel drive and a 4.3 L six-cylinder engine. Its MPG figures, emissions and annual fuel cost are useful for comparing operating expenses.

What is good

  • Cargo-type van classification
  • Rear-wheel drive
  • 20 MPG highway fuel economy
  • EPA annual fuel cost listed

What to know first

  • 15 MPG city fuel economy
  • 17 MPG combined
  • $3,950 annual fuel cost

CarCody review

2000 GMC Safari 2WD (cargo): the full review

The Safari 2WD cargo entry combines a 4.3 L six-cylinder engine with a four-speed automatic and rear-wheel drive. Buyers comparing fuel use should note its 17 MPG combined rating and $3,950 EPA annual fuel cost.

Overview

The 2000 GMC Safari 2WD (cargo) is a gasoline-powered cargo van in the Vans, Cargo Type EPA class. Its rear-wheel-drive layout pairs a 4.3-liter six-cylinder engine with a four-speed automatic transmission. EPA fuel economy is 15 mpg in the city, 20 mpg on the highway and 17 mpg combined.

Those figures provide a useful baseline for buyers comparing older cargo vans and estimating fuel use. The EPA lists annual fuel cost at $3,950 and tailpipe carbon dioxide emissions at 522.76 grams per mile. Actual costs depend on fuel prices and driving, so the listed annual figure is best treated as an estimate rather than a guarantee.

See GMC cars for more models from the make.

Key features

  • Body and class: Van; EPA class is Vans, Cargo Type.
  • Powertrain: 4.3-liter six-cylinder gasoline engine and four-speed automatic transmission.
  • Drivetrain: Rear-wheel drive.
  • EPA fuel economy: 15 mpg city, 20 mpg highway and 17 mpg combined.
  • EPA running-cost and emissions figures: $3,950 annual fuel cost and 522.76 g/mile tailpipe CO2.

Who it's for

The Safari Cargo is relevant to shoppers evaluating a gasoline cargo van with rear-wheel drive and a conventional automatic transmission. Its EPA city, highway and combined ratings help set fuel-use expectations, while the annual fuel-cost estimate and tailpipe CO2 figure add two points of comparison for fleet operators and buyers weighing operating costs. The supplied figures describe fuel economy and emissions; they do not establish cargo capacity, condition, reliability or suitability for a particular job.

Pros and cons

Pros

  • EPA city, highway and combined ratings give a clear fuel-economy reference.
  • The rear-wheel-drive configuration, six-cylinder gasoline engine and automatic transmission are specified.
  • Annual fuel cost and tailpipe CO2 are stated alongside fuel economy.

Cons

  • The combined EPA rating is 17 mpg, with a 15 mpg city rating.
  • The listed annual fuel cost is $3,950, and the EPA tailpipe CO2 figure is 522.76 g/mile.
  • The available specifications do not provide cargo volume, payload, purchase price or detailed equipment information.

Alternatives

For a current GMC comparison, consider the 2027 GMC Acadia AWD or 2027 GMC Acadia FWD. Other options include the 2027 GMC Terrain AWD, 2027 GMC Terrain AWD Denali/AT4 and 2027 GMC Terrain FWD. Shoppers considering a larger GMC can compare the 2027 GMC Yukon 2WD, another 2027 GMC Yukon 2WD listing and a further 2027 GMC Yukon 2WD listing. The supplied details here do not include specifications for those alternatives, so a direct fuel-economy comparison requires their respective ratings.

Verdict

The 2000 GMC Safari 2WD (cargo) has a clearly defined powertrain and EPA profile: a 4.3-liter gasoline V6, four-speed automatic, rear-wheel drive and 17 mpg combined. The $3,950 annual fuel-cost estimate and 522.76 g/mile tailpipe CO2 rating make fuel use and emissions central considerations. Buyers should compare those figures with their expected driving and check for the other specifications needed to judge a particular van, especially cargo and payload requirements.

Details

Model year
2000fueleconomy.gov · 3 Oct 2026

Efficiency

Combined MPG
17fueleconomy.gov · 3 Oct 2026
City MPG
15fueleconomy.gov · 3 Oct 2026
Highway MPG
20fueleconomy.gov · 3 Oct 2026

Running cost

Annual fuel cost
$3,950fueleconomy.gov · 3 Oct 2026
CO₂ (tailpipe)
522.8 g/mifueleconomy.gov · 3 Oct 2026

Car

Body
Vanfueleconomy.gov · 3 Oct 2026
EPA class
Vans, Cargo Typefueleconomy.gov · 3 Oct 2026
Drive
Rear-Wheel Drivefueleconomy.gov · 3 Oct 2026

Powertrain

Engine
4.3 L 6-cylfueleconomy.gov · 3 Oct 2026
Transmission
Automatic 4-spdfueleconomy.gov · 3 Oct 2026
Fuel
Gasolinefueleconomy.gov · 3 Oct 2026

More GMC cars

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Sources